The U.S. Food and Drug Administration (FDA) has announced that a preliminary review of popular diabetes and obesity drugs, including Ozempic, Wegovy, and Mounjaro, has found no link to suicidal thoughts or actions[^1^]. While the agency acknowledges that a small risk cannot be definitively ruled out, it assures patients that there is currently no evidence to suggest that these medications cause any harm. However, the FDA will continue to investigate reports concerning these drugs[^1^].
Semaglutide: A Promising Option
The FDA’s review was prompted by anecdotal reports from European regulators regarding semaglutide, the main component of both Ozempic and Wegovy. These reports suggested that individuals taking semaglutide may experience thoughts of self-harm. However, a recent study funded by the federal government contradicted these claims, revealing that people on semaglutide actually had a lower risk of suicidal thoughts compared to those on other medications for obesity and diabetes[^1^].
GLP-1 Receptor Agonists Under Scrutiny
The FDA review extends beyond Ozempic and Wegovy to cover more than a dozen drugs known as GLP-1 receptor agonists. These medications are commonly prescribed to manage blood sugar levels and reduce the risk of heart disease in individuals with type 2 diabetes. Some of these drugs are also used to aid weight loss in those who are overweight or obese[^1^].
Patient Safety First
While the FDA emphasizes that there is currently no evidence linking these drugs to suicidal thoughts or actions, it encourages patients to inform their healthcare providers if they have any concerns. Open communication is vital when it comes to managing medications and ensuring patient safety. Therefore, if any worries arise, do not hesitate to reach out to your healthcare professional[^1^].
Remember, if you or someone you know is in crisis, immediate help is available. You can call or text 988 to reach the Suicide and Crisis Lifeline, or chat live at 988lifeline.org. Additional support can also be found at SpeakingOfSuicide.com/resources[^1^].
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Source: Drugs like Ozempic and Wegovy show no link with suicide, FDA says
[^1^]: NBC News. (n.d.). Drugs like Ozempic and Wegovy show no link with suicide, FDA says. Retrieved from https://www.nbcnews.com/health/health-news/drugs-ozempic-wegovy-show-no-link-suicide-fda-says-rcna133537